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BCAA vid cancer och ALS

Beth Israel Deaconess Medical Center (BIDMC) är en av USA:S ledande akademiska sjukhus och forskningscenter. Som ett universitetssjukhus inom Harvard Medical School är BIDMC ett av världens ledande center inom hälsa och sjukvård. De skriver på sin hemsida: ”Grenade aminosyror (BCAA) är naturligt förekommande molekyler/aminosyror (leucin, isoleucin och valin) som kroppen använder för att bygga proteiner.

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Fakta och myter – Vitamin B12 (kobalamin)

S. J. Moore, A. D. Lawrence, R. Biedendieck, E. Deery, S. Frank, M. J. Howard, S. E. J. Rigby, M. J. Warren. Elucidation of the anaerobic pathway for the corrin component of cobalamin (vitamin B12). Proceedings of the National Academy of Sciences, 2013; DOI: 10.1073/pnas.1308098110 Länk

Watson WS, Vallance BD, Muir MM, Hume R. The effect of megadose ascorbic acid ingestion on the absorption and retention of vitamin B12 in man. Scott Med J. 1982 Jul;27(3):240-3. 

Dagnelie PC, van Staveren WA, van den Berg H. Vitamin B-12 from algae appears not to be bioavailable. Am J Clin Nutr. 1991 Mar;53(3):695-7. 

Herbert V. Vitamin B-12: plant sources, requirements, and assay. Am J Clin Nutr. 1988 Sep;48(3 Suppl):852-8. doi: 10.1093/ajcn/48.3.852.

Patterson N, Richter DJ, Gnerre S, Lander ES, Reich D. Genetic evidence for complex speciation of humans and chimpanzees. Nature. 2006 Jun 29;441(7097):1103-8. Epub 2006 May 17.

Zhang Y, Hodgson NW, Trivedi MS, et al. Decreased Brain Levels of Vitamin B12 in Aging, Autism and Schizophrenia. PLoS One. 2016;11(1):e0146797. Published 2016 Jan 22. doi:10.1371/journal.pone.0146797.

Carmel R. A new case of deficiency of the R binder for cobalamin, with observations on minor cobalamin-binding proteins in serum and saliva. Blood. 1982 Jan;59(1):152-6.

Staff NP, Windebank AJ. Peripheral neuropathy due to vitamin deficiency, toxins, and medications. Continuum (Minneap Minn). 2014 Oct;20(5 Peripheral Nervous System Disorders):1293-306. doi: 10.1212/01.CON.0000455880.06675.5a. 

Miyamoto E, Tanioka Y, Nakao T, Barla F, Inui H, Fujita T et al. Purification and characterization of a corrinoid-compound in an edible cyanobacterium Aphanizomenon flos-aquae as a nutritional supplementary food. J Agric Food Chem. 2006 Dec 13;54(25):9604-7.

Michael R. Dobbs (ed). Clinical Neurotoxicology. Philadelphia, Elsevier; 2009. 

Watanabe F, Takenaka S, Kittaka-Katsura H, Ebara S, Miyamoto E. Characterization and bioavailability of vitamin B12-compounds from edible algae. J Nutr Sci Vitaminol (Tokyo). 2002 Oct;48(5):325-31.

O'Leary F, Samman S. Vitamin B12 in health and disease. Nutrients. 2010 Mar;2(3):299-316. doi: 10.3390/nu2030299. Epub 2010 Mar 5.

Pawlak R, Lester SE, Babatunde T. The prevalence of cobalamin deficiency among vegetarians assessed by serum vitamin B12: a review of literature. Eur J Clin Nutr. 2016 Jul;70(7):866. doi: 10.1038/ejcn.2016.81.

Paul C, Brady DM. Comparative Bioavailability and Utilization of Particular Forms of B12 Supplements With Potential to Mitigate B12-related Genetic Polymorphisms. Integr Med (Encinitas). 2017 Feb;16(1):42-49.

Huan Fang, Jie Kang, Dawei Zhang. Microbial production of vitamin B12: a review and future perspectives. Microb Cell Fact. 2017; 16: 15. Published online 2017 Jan 30. doi: 10.1186/s12934-017-0631-y  

Halsted JA, Caroll J, Rubert S. Serum and tissue concentration of vitamin B12 in certain pathologic states. N Engl J Med. 1959 Mar 19;260(12):575-80.

Kornerup LS, Fedosov SN, Juul CB, Greibe E, Heegaard CW, Nexo E. Tissue distribution of oral vitamin B12 is influenced by B12 status and B12 form: an experimental study in rats. Eur J Nutr. 2018 Jun;57(4):1459-1469. doi: 10.1007/s00394-017-1424-0. Epub 2017 Mar 20. 

Li S, Sun L, Qi L, Jia Y, Cui Z, Wang Z, Li F, Zhao X. Effect of high homocysteine level on the severity of coronary heart disease and prognosis after stent implantation. J Cardiovasc Pharmacol. 2020 Mar 18. doi: 10.1097/FJC.0000000000000829. 

Esnafoglu E, Ozturan DD. The relationship of severity of depression with homocysteine, folate, vitamin B12, and vitamin D levels in children and adolescents. Child Adolesc Ment Health. 2020 Apr 18. doi: 10.1111/camh.12387. 

Liampas I, Siokas V, Aloizou A, Tsouris Z, Metaxia D, Aslanidou P, Brotis A, Dardiotis E. Pyridoxine, folate and cobalamin for migraine: A Systematic Review. Acta Neurol Scand. 2020 Apr 12. doi: 10.1111/ane.13251.

Paul C, Brady DM. Comparative Bioavailability and Utilization of Particular Forms of B12 Supplements With Potential to Mitigate B12-related Genetic Polymorphisms. Integr Med (Encinitas). 2017 Feb;16(1):42-49.

Chen S, Honda T, Ohara T, Hata J, Hirakawa Y, Yoshida D et al. Serum homocysteine and risk of dementia in Japan. J Neurol Neurosurg Psychiatry. 2020 May;91(5):540-546. doi: 10.1136/jnnp-2019-322366. Epub 2020 Mar 31.

Cao L, Guo Y, Zhu Z. Effects of hyperhomocysteinemia on ischemic cerebral small vessel disease and analysis of inflammatory mechanisms. Int J Neurosci. 2020 Apr 1:1-8. doi: 10.1080/00207454.2020.1744597.

You ZP, Zhang YZ, Zhang YL, Shi L, Shi K. Homocysteine induces oxidative stress to damage trabecular meshwork cells. Exp Ther Med. 2018 May;15(5):4379-4385. doi: 10.3892/etm.2018.5961. 

Varga EA, Sturm AC, Misita CP & Moll S. Homocysteine and MTHFR Mutations: Relation to Thrombosis and Coronary Artery Disease. Circulation. 2005; 111:e289-e293.

Dean L. Methylenetetrahydrofolate Reductase Deficiency. Medical Genetics Summaries. NCBI; Last updated October 27, 2016

Glutamin – tarmens bästa vän

[1] J Nutr. 2008 Oct;138(10):2045S-2049S. Dosing and efficacy of glutamine supplementation in human exercise and sport training. Gleeson M.

[2] JPEN J Parenter Enteral Nutr. 2003 Mar-Apr;27(2):116-22. Glutamine preserves cardiomyocyte viability and enhances recovery of contractile function after ischemia-reperfusion injury.

[3] Life Sci. 2007 Apr 24;80(20):1846-50. Epub 2007 Feb 22. Association between glutamine extraction and release of citrulline and glycine by the human small intestine. Fujita T, Yanaga K.

[4] Acta Physiol Scand. 2001 May;172(1):1-10. Glutathione deficiency intensifies ischaemia-reperfusion induced cardiac dysfunction and oxidative stress. Leichtweis S, Ji LL.

[5] Nutrition. 2002 Feb;18(2):123-6. Is glutamine beneficial in ischemic heart disease? Khogali SE, Pringle SD, Weryk BV, Rennie MJ.

[6] Nutrition. 2011 Sep;27(9):938-42. doi: 10.1016/j.nut.2010.08.025. Epub 2010 Dec 3. A randomized cross-over study of the metabolic and hormonal responses following two preoperative conditioning drinks.

[7] Biochem J. 1983 Jun 15;212(3):835-42. Glutamine metabolism in lymphocytes of the rat. Ardawi MS, Newsholme EA.

[8] FEBS Lett. 1988 Sep 12;237(1-2):133-6. Inhibition of protein breakdown by glutamine in perfused rat skeletal muscle. MacLennan PA, Smith K, Weryk B, Watt PW, Rennie MJ.

[9] FEBS Lett. 1987 May 4;215(1):187-91. A positive relationship between protein synthetic rate and intracellular glutamine concentration in perfused rat skeletal muscle. MacLennan PA, Brown RA, Rennie MJ.

[10] American Journal of Physiology - Endocrinology and MetabolismPublished 1 October 1996Vol. 271no. E748-E754. Effect of glutamine on leucine metabolism in humans R. G. Hankard , M. W. Haymond , D. Darmaun

[11] Eur J Appl Physiol. 2008 Jun;103(3):289-94. doi: 10.1007/s00421-008-0702-1. Epub 2008 Mar 5. Effects of exercise on leukocyte death: prevention by hydrolyzed whey protein enriched with glutamine dipeptide. Cury-Boaventura MF, Levada-Pires AC, Folador A, Gorjão R, Alba-Loureiro TC, Hirabara SM, Peres FP, Silva PR, Curi R, Pithon-Curi TC.

[12] Am J Physiol Endocrinol Metab. 2000 May;278(5):E817-24. Effect of enteral glutamine on leucine, phenylalanine and glutamine metabolism in hypercortisolemic subjects. 

[13] Am J Physiol Gastrointest Liver Physiol. 2004 Sep;287(3):G726-33. Epub 2004 May 6. Glutamine regulates Caco-2 cell tight junction proteins. Li N, Lewis P, Samuelson D, Liboni K, Neu J.

[14] Pediatr Res. 2002 Sep;52(3):430-6. Glutamine supplementation and deprivation: effect on artificially reared rat small intestinal morphology. Potsic B, Holliday N, Lewis P, Samuelson D, DeMarco V, Neu J.

[15] J. Nutr. July 1, 2003 vol. 133 no. 7 2176-2179 . Glutamine and Barrier Function in Cultured Caco-2 Epithelial Cell Monolayers Vincent G. DeMarco, Nan Li, Justin Thomas, Christopher M. West, and Josef Neu

[16] Internet http://www.dailyperricone.com/2009/01/targeted-foods-and-supplements-for-healthy-slimming/

[17] Barchitta M, Maugeri A, Favara G, Magnano San Lio R, Evola G, Agodi A, Basile G. Nutrition and Wound Healing: An Overview Focusing on the Beneficial Effects of Curcumin. Int J Mol Sci. 2019 Mar 5;20(5).

MegaFlora Kids – Probiotika

Hickson M, D'Souza AL, Muthu N, Rogers TR, Want S, Rajkumar C et al. Use of probiotic Lactobacillus preparation to prevent diarrhoea associated with antibiotics: randomised double blind placebo controlled trial.BMJ. 2007 Jul 14;335(7610):80. Epub 2007 Jun 29.

D'Souza AL, Rajkumar C, Cooke J, Bulpitt CJ. Probiotics in prevention of antibiotic associated diarrhoea: meta-analysis. BMJ. 2002 Jun 8;324(7350):1361.

Armuzzi A, Cremonini F, Bartolozzi F, Canducci F, Candelli M, Ojetti V et al. The effect of oral administration of Lactobacillus GG on antibiotic-associated gastrointestinal side-effects during Helicobacter pylori eradication therapy. Aliment Pharmacol Ther. 2001 Feb;15(2):163-9.

Cremonini F, Di Caro S, Nista EC, Bartolozzi F, Capelli G, Gasbarrini G et al. Meta-analysis: the effect of probiotic administration on antibiotic-associated diarrhoea. Aliment Pharmacol Ther. 2002 Aug;16(8):1461-7.

Sazawal S, Hiremath G, Dhingra U, Malik P, Deb S, Black RE. Efficacy of probiotics in prevention of acute diarrhoea: a meta-analysis of masked, randomised, placebo-controlled trials. Lancet Infect Dis. 2006 Jun;6(6):374-82.

Iva Hojsak. Probiotics in Children: What Is the Evidence? Pediatr Gastroenterol Hepatol Nutr. 2017 Sep; 20(3): 139–146.

MegaFlora – Probiotika

Hickson M, D'Souza AL, Muthu N, Rogers TR, Want S, Rajkumar C et al. Use of probiotic Lactobacillus preparation to prevent diarrhoea associated with antibiotics: randomised double blind placebo controlled trial.BMJ. 2007 Jul 14;335(7610):80. Epub 2007 Jun 29.

D'Souza AL, Rajkumar C, Cooke J, Bulpitt CJ. Probiotics in prevention of antibiotic associated diarrhoea: meta-analysis. BMJ. 2002 Jun 8;324(7350):1361.

Armuzzi A, Cremonini F, Bartolozzi F, Canducci F, Candelli M, Ojetti V et al. The effect of oral administration of Lactobacillus GG on antibiotic-associated gastrointestinal side-effects during Helicobacter pylori eradication therapy. Aliment Pharmacol Ther. 2001 Feb;15(2):163-9.

Cremonini F, Di Caro S, Nista EC, Bartolozzi F, Capelli G, Gasbarrini G et al. Meta-analysis: the effect of probiotic administration on antibiotic-associated diarrhoea. Aliment Pharmacol Ther. 2002 Aug;16(8):1461-7.

Sazawal S, Hiremath G, Dhingra U, Malik P, Deb S, Black RE. Efficacy of probiotics in prevention of acute diarrhoea: a meta-analysis of masked, randomised, placebo-controlled trials. Lancet Infect Dis. 2006 Jun;6(6):374-82.

Jean-Claude Rambaud (ed.), Jean-Paul Buts (ed.), Gerard Corthier (ed.), Bernard Flourie (ed.). Gut Microflora: Digestive Physiology and Pathology. Paris: John Libbey Eurotext; 2006.

Ohman L, Simrén M. Pathogenesis of IBS: role of inflammation, immunity and neuroimmune interactions. Nature Reviews Gastroenterology & Hepatology. 2010 Mar;7(3):163-73.

MegaFlora Women – Probiotika

Bertuccini L, Russo R, Iosi F, Superti F. Effects of Lactobacillus rhamnosus and Lactobacillus acidophilus on bacterial vaginal pathogens. Int J Immunopathol Pharmacol. 2017;30(2):163‐167. doi:10.1177/0394632017697987

Hickson M, D'Souza AL, Muthu N, Rogers TR, Want S, Rajkumar C et al. Use of probiotic Lactobacillus preparation to prevent diarrhoea associated with antibiotics: randomised double blind placebo controlled trial.BMJ. 2007 Jul 14;335(7610):80. Epub 2007 Jun 29.

D'Souza AL, Rajkumar C, Cooke J, Bulpitt CJ. Probiotics in prevention of antibiotic associated diarrhoea: meta-analysis. BMJ. 2002 Jun 8;324(7350):1361.

Armuzzi A, Cremonini F, Bartolozzi F, Canducci F, Candelli M, Ojetti V et al. The effect of oral administration of Lactobacillus GG on antibiotic-associated gastrointestinal side-effects during Helicobacter pylori eradication therapy. Aliment Pharmacol Ther. 2001 Feb;15(2):163-9.

Cremonini F, Di Caro S, Nista EC, Bartolozzi F, Capelli G, Gasbarrini G et al. Meta-analysis: the effect of probiotic administration on antibiotic-associated diarrhoea. Aliment Pharmacol Ther. 2002 Aug;16(8):1461-7.

Sazawal S, Hiremath G, Dhingra U, Malik P, Deb S, Black RE. Efficacy of probiotics in prevention of acute diarrhoea: a meta-analysis of masked, randomised, placebo-controlled trials. Lancet Infect Dis. 2006 Jun;6(6):374-82.

Jean-Claude Rambaud (ed.), Jean-Paul Buts (ed.), Gerard Corthier (ed.), Bernard Flourie (ed.). Gut Microflora: Digestive Physiology and Pathology. Paris: John Libbey Eurotext; 2006.

Ohman L, Simrén M. Pathogenesis of IBS: role of inflammation, immunity and neuroimmune interactions. Nature Reviews Gastroenterology & Hepatology. 2010 Mar;7(3):163-73.

MegaFlora for Baby & Me – Probiotika

Slykerman RF, Hood F, Wickens K, et al. Effect of Lactobacillus rhamnosus HN001 in Pregnancy on Postpartum Symptoms of Depression and Anxiety: A Randomised Double-blind Placebo-controlled Trial. EBioMedicine. 2017;24:159‐165. doi:10.1016/j.ebiom.2017.09.013

Wickens K, Barthow C, Mitchell EA, et al. Effects of Lactobacillus rhamnosus HN001 in early life on the cumulative prevalence of allergic disease to 11 years. Pediatr Allergy Immunol. 2018;29(8):808‐814. doi:10.1111/pai.12982

Wickens KL, Barthow CA, Murphy R, et al. Early pregnancy probiotic supplementation with Lactobacillus rhamnosus HN001 may reduce the prevalence of gestational diabetes mellitus: a randomised controlled trial. Br J Nutr. 2017;117(6):804‐813. doi:10.1017/S0007114517000289

Edwards SM, Cunningham SA, Dunlop AL, Corwin EJ. The Maternal Gut Microbiome During Pregnancy. MCN Am J Matern Child Nurs. 2017;42(6):310‐317. doi:10.1097/NMC.0000000000000372

Bertuccini L, Russo R, Iosi F, Superti F. Effects of Lactobacillus rhamnosus and Lactobacillus acidophilus on bacterial vaginal pathogens. Int J Immunopathol Pharmacol. 2017;30(2):163‐167. doi:10.1177/0394632017697987

Hickson M, D'Souza AL, Muthu N, Rogers TR, Want S, Rajkumar C et al. Use of probiotic Lactobacillus preparation to prevent diarrhoea associated with antibiotics: randomised double blind placebo controlled trial.BMJ. 2007 Jul 14;335(7610):80. Epub 2007 Jun 29.

D'Souza AL, Rajkumar C, Cooke J, Bulpitt CJ. Probiotics in prevention of antibiotic associated diarrhoea: meta-analysis. BMJ. 2002 Jun 8;324(7350):1361.

Armuzzi A, Cremonini F, Bartolozzi F, Canducci F, Candelli M, Ojetti V et al. The effect of oral administration of Lactobacillus GG on antibiotic-associated gastrointestinal side-effects during Helicobacter pylori eradication therapy. Aliment Pharmacol Ther. 2001 Feb;15(2):163-9.

Cremonini F, Di Caro S, Nista EC, Bartolozzi F, Capelli G, Gasbarrini G et al. Meta-analysis: the effect of probiotic administration on antibiotic-associated diarrhoea. Aliment Pharmacol Ther. 2002 Aug;16(8):1461-7.

Sazawal S, Hiremath G, Dhingra U, Malik P, Deb S, Black RE. Efficacy of probiotics in prevention of acute diarrhoea: a meta-analysis of masked, randomised, placebo-controlled trials. Lancet Infect Dis. 2006 Jun;6(6):374-82.

Jean-Claude Rambaud (ed.), Jean-Paul Buts (ed.), Gerard Corthier (ed.), Bernard Flourie (ed.). Gut Microflora: Digestive Physiology and Pathology. Paris: John Libbey Eurotext; 2006.

Ohman L, Simrén M. Pathogenesis of IBS: role of inflammation, immunity and neuroimmune interactions. Nature Reviews Gastroenterology & Hepatology. 2010 Mar;7(3):163-73.

Astaxantin - Superämne för mer än bara vacker hud

[1] J Nutr Biochem. 2010 May;21(5):381-9. Astaxanthin protects mitochondrial redox state and functional integrity against oxidative stress. Wolf AM, Asoh S, Hiranuma H, Ohsawa I, Iio K, Satou A, Ishikura M, Ohta S.Department of Biochemistry and Cell Biology, Institute of Development and Aging Sciences, Nippon Medical School, Nakahara-ku, Kawasaki, Kanagawa, Japan.http://www.ncbi.nlm.nih.gov/pubmed/19423317

[2] Exp Dermatol. 2012 Jul;21 Suppl 1:11-7. Astaxanthin attenuates the UVB-induced secretion of prostaglandin E2 and interleukin-8 in human keratinocytes by interrupting MSK1 phosphorylation in a ROS depletion-independent manner. Terazawa S, Nakajima H, Shingo M, Niwano T, Imokawa G. School of Bioscience and Biotechnology, Tokyo University of Technology, Hachioji, Tokyo, Japan. kimura@nagahp.jp http://www.ncbi.nlm.nih.gov/pubmed/22626465

[3] Asian J Androl. 2005 Sep;7(3):257-62. Combined conventional/antioxidant "Astaxanthin" treatment for male infertility: a double blind, randomized trial. Comhaire FH, El Garem Y, Mahmoud A, Eertmans F, Schoonjans F. Ghent University Hospital, Department of Medical and Urological Andrology, 9k12 IE, De Pintelaan, 185, B 9000, Gent, Belgium. http://www.ncbi.nlm.nih.gov/pubmed/16110353

[4] Altern Med Rev. 2011 Dec;16(4):355-64. Astaxanthin, cell membrane nutrient with diverse clinical benefits and anti-aging potential. Kidd P. University of California, Berkeley, CA, USA. http://www.ncbi.nlm.nih.gov/pubmed/22214255

[5] J Atheroscler Thromb. 2000;7(4):216-22. Inhibition of low-density lipoprotein oxidation by astaxanthin. Iwamoto T, Hosoda K, Hirano R, Kurata H, Matsumoto A, Miki W, Kamiyama M, Itakura H, Yamamoto S, Kondo K. National Institute of Health and Nutrition, Tokyo, Japan.http://www.ncbi.nlm.nih.gov/pubmed/11521685

[6] Br J Nutr. 2011 Jun;105(11):1563-71. Antioxidant effect of astaxanthin on phospholipid peroxidation in human erythrocytes. Nakagawa K, Kiko T, Miyazawa T, Carpentero Burdeos G, Kimura F, Satoh A, Miyazawa T. Food and Biodynamic Chemistry Laboratory, Graduate School of Agricultural Science, Tohoku University, Sendai 981-8555, Japan.http://www.ncbi.nlm.nih.gov/pubmed/21276280

[7] Atherosclerosis. 2010 Apr;209(2):520-3. Administration of natural astaxanthin increases serum HDL-cholesterol and adiponectin in subjects with mild hyperlipidemia. Yoshida H, Yanai H, Ito K, Tomono Y, Koikeda T, Tsukahara H, Tada N. Department of Laboratory Medicine, Jikei University Kashiwa Hospital, Chiba, Japan.http://www.ncbi.nlm.nih.gov/pubmed/19892350

[8] J Sports Med Phys Fitness. 2012 Aug;52(4):382-92. Effect of astaxanthin supplementation on muscle damage and oxidative stress markers in elite young soccer players. Djordjevic B, Baralic I, Kotur-Stevuljevic J, Stefanovic A, Ivanisevic J, Radivojevic N, Andjelkovic M, Dikic N. Institute for Bromatology, University of Belgrade, Belgrade, Serbia. http://www.ncbi.nlm.nih.gov/pubmed/23192897

[9] Int Immunopharmacol. 2011 Dec;11(12):2220-6. Impact of the carotenoid astaxanthin on phagocytic capacity and ROS/RNS production of human neutrophils treated with free fatty acids and high glucose. Guerra BA, Otton R. Postgraduate Program-Health Sciences-CBS, Cruzeiro do Sul University, Sao Paulo, SP, 03342000, Brazil. http://www.ncbi.nlm.nih.gov/pubmed/22008307

[10] Toxicol In Vitro. 2011 Oct;25(7):1448-56. Oxidative stress in human lymphocytes treated with fatty acid mixture: role of carotenoid astaxanthin. Campoio TR, Oliveira FA, Otton R. Postgraduate Program - Health Sciences - CBS, Cruzeiro do Sul University, 03342000 Sao Paulo, SP, Brazil.

[11] Acta Biochim Pol. 2012;59(1):43-7. Cosmetic benefits of astaxanthin on humans subjects. Tominaga K, Hongo N, Karato M, Yamashita E. Fuji Chemical Industry Co. Ltd., Kamiichi, Toyama, Japan.

Artikelkälla: http://www.wellnessresources.com/health/articles/astaxanthin_a_premium_cell_defense_nutrient/

Quercetin skyddar mot vanligt bakteriegift

Zhongguo Dang Dai Er Ke Za Zhi. 2006 Oct;8(5):425-8. [Protective effects of recombinant intestinal trefoil factor against intestinal injuries induced by endotoxin in young rats]. Li J, Xu LF, Sun M, Li Q, Gao H, Jiang WG.

Res Exp Med (Berl). 1986;186(1):61-9. Lipopolysaccharide-induced colitis in rabbits. Hotta T, Yoshida N, Yoshikawa T, Sugino S, Kondo M.

Acta Med Okayama. 1978 Jul;32(3):207-16. A study of endotoxemia in ulcerative colitis and Crohn's disease. II. Experimental study. Aoki K.

Transplant Proc. 2006 Jul-Aug;38(6):1815-7. The role of dendritic cells in the gastrointestinal field effect. Koscielny A, Boerner T, Wehner S, Kurts C, Kalff JC.

Arch Surg. 1995 Jan;130(1):53-8. The effect of endotoxin on intestinal mucosal permeability to bacteria in vitro. Go LL, Healey PJ, Watkins SC, Simmons RL, Rowe MI.

J Clin Invest. 1988 Nov;82(5):1714-21. Bacterial lipopolysaccharide-induced intestinal microvascular lesions leading to acute diarrhea. Mathan VI, Penny GR, Mathan MM, Rowley D.

Hepatology. 2009 May;49(5):1545-53. doi: 10.1002/hep.22847. Fibrin accumulation plays a critical role in the sensitization to lipopolysaccharide-induced liver injury caused by ethanol in mice. Beier JI, Luyendyk JP, Guo L, von Montfort C, Staunton DE, Arteel GE.

Thromb Res. 2013 Jun;131(6):e270-3. doi: 10.1016/j.thromres.2013.03.002. Epub 2013 Apr 6. Effects of quercetin on LPS-induced disseminated intravascular coagulation (DIC) in rabbits. Yu PX, Zhou QJ, Zhu WW, Wu YH, Wu LC, Lin X, Chen MH, Qiu BT.

Fem tips för att inte bränna huden i sommar!

Brian J. Hall MD (ed.), John C. Hall MD (ed.). Sauer’s Manual of Skin Diseases. 10th ed. Philadelphia: Lippincott Williams & Wilkins; 2010.

Pilkington SM, Watson RE, Nicolaou A, Rhodes LE. Omega-3 polyunsaturated fatty acids: photoprotective macronutrients. Experimental Dermatology. 2011 Jul;20(7):537-43.

Liu G, Bibus DM, Bode AM, Ma WY, Holman RT, Dong Z. Omega 3 but not omega 6 fatty acids inhibit AP-1 activity and cell transformation in JB6 cells. Proceedings of the National Academy of Sciences. 2001 Jun 19;98(13):7510-5.

Lester Packer (ed.), Maret G Traber (r.ed), Klaus Kraemer (ed.), Balz Frei (ed.). The Antioxidant Vitamins C and E. Champaign: AOCS Press; 2002.

Enrique Cadenas (ed.), Lester Packer (ed.). Handbook of Antioxidants. New York: Marcel Dekker; 2002.

Rodríguez-Yanes E, Juarranz Á, Cuevas J, Gonzalez S, Mallol J. Polypodium leucotomos decreases UV-induced epidermal cell proliferation and enhances p53 expression and plasma antioxidant capacity in hairless mice. Experimental Dermatology. 2012 Aug;21(8):638-40.

Poljšak B, Dahmane R. Free radicals and extrinsic skin aging. Dermatology Research and Practice. 2012;2012:135206.

Rao AR, Sindhuja HN, Dharmesh SM, Sankar KU, Sarada R, Ravishankar GA. Effective inhibition of skin cancer, tyrosinase, and antioxidative properties by astaxanthin and astaxanthin esters from the green alga Haematococcus pluvialis. Journal of Agricultural and Food Chemistry. 2013 Apr 24;61(16):3842-51.

Maoka T, Tokuda H, Suzuki N, Kato H, Etoh H. Anti-oxidative, anti-tumor-promoting, and anti-carcinogensis activities of nitroastaxanthin and nitrolutein, the reaction products of astaxanthin and lutein with peroxynitrite. Marine Drugs. 2012 Jun;10(6):1391-9.

Bens G. Sunscreens. Advances in Experimental Medicine and Biology. 2014;810:429-63.

Lídia Palma, Liliana Tavares Marques, Julia Bujan, Luís Monteiro Rodrigues. Clin Cosmet Investig Dermatol. Dietary water affects human skin hydration and biomechanics
2015; 8: 413–421.

Lyons NM1, O'Brien NM. Modulatory effects of an algal extract containing astaxanthin on UVA-irradiated cells in culture. J Dermatol Sci. 2002 Oct;30(1):73-84.

David G. Hoel,a Marianne Berwick,b Frank R. de Gruijl,c and Michael F. Holick D. The risks and benefits of sun exposure 2016. Dermatoendocrinol. 2016 Jan-Dec; 8(1): e1248325.

Alzheimers – näring och livsstil vid kognitiva sjukdomar

Alzheimer’s Association. 2015 Alzheimer's disease facts and figures. Alzheimers Dement. 2015;11(3):332-384. doi:10.1016/j.jalz.2015.02.003

Demenssjukdomarnas Samhällskostnader i Sverige 2012. Socialstyrelsen. 

Calsolaro V, Edison P. Neuroinflammation in Alzheimer's disease: Current evidence and future directions. Alzheimers Dement. 2016;12(6):719-732. doi:10.1016/j.jalz.2016.02.010

Moore E, Mander A, Ames D, Carne R, Sanders K, Watters D. Cognitive impairment and vitamin B12: a review. Int Psychogeriatr. 2012;24(4):541-556. doi:10.1017/S1041610211002511

Boston PF, McKirdy SJ, Al-Turki MA, Barker ME, Russell JM. Vitamin B12 and folate levels in progression of Alzheimer's disease - a short report. Int J Psychiatry Clin Pract. 2020;24(1):68-70. doi:10.1080/13651501.2019.1681457

Athanasopoulos D, Karagiannis G, Tsolaki M. Recent Findings in Alzheimer Disease and Nutrition Focusing on Epigenetics. Adv Nutr. 2016;7(5):917-927. Published 2016 Sep 15. doi:10.3945/an.116.012229

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